Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

Stable genetic modification of adult stem cells is fundamental for both developmental studies and therapeutic purposes. Using in vivo marking studies, we showed that injection of lentiviral vectors (LVs) into the subventricular zone of the adult mouse brain enables efficient gene transfer into long-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Consiglio, Antonella, Gritti, Angela, Dolcetta, Diego, Follenzi, Antonia, Bordignon, Claudio, Gage, Fred H., Vescovi, Angelo Luigi, Naldini, Luigi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC522006/
https://ncbi.nlm.nih.gov/pubmed/15466696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404180101
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