The Old and the New: Prospects for Non-Integrating Lentiviral Vector Technology

Lentiviral vectors have been developed and used in multiple gene and cell therapy applications. One of their main advantages over other vectors is the ability to integrate the genetic material into the genome of the host. However, this can also be a disadvantage as it may lead to insertional mutagen...

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Hlavní autor:	Luis Apolonia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-09-01
Edice:	Viruses
Témata:	lentiviral vectors non-integrating lentiviral vectors (NILVs) insertional mutagenesis transgene expression immunotherapy CRISPR/Cas9
On-line přístup:	https://www.mdpi.com/1999-4915/12/10/1103
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