The Old and the New: Prospects for Non-Integrating Lentiviral Vector Technology

Lentiviral vectors have been developed and used in multiple gene and cell therapy applications. One of their main advantages over other vectors is the ability to integrate the genetic material into the genome of the host. However, this can also be a disadvantage as it may lead to insertional mutagen...

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Detalles Bibliográficos

Autor principal:	Luis Apolonia
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2020-09-01
Colección:	Viruses
Materias:	lentiviral vectors non-integrating lentiviral vectors (NILVs) insertional mutagenesis transgene expression immunotherapy CRISPR/Cas9
Acceso en línea:	https://www.mdpi.com/1999-4915/12/10/1103
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