Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

Stable genetic modification of adult stem cells is fundamental for both developmental studies and therapeutic purposes. Using in vivo marking studies, we showed that injection of lentiviral vectors (LVs) into the subventricular zone of the adult mouse brain enables efficient gene transfer into long-...

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Detalles Bibliográficos
Autores principales: Consiglio, Antonella, Gritti, Angela, Dolcetta, Diego, Follenzi, Antonia, Bordignon, Claudio, Gage, Fred H., Vescovi, Angelo Luigi, Naldini, Luigi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC522006/
https://ncbi.nlm.nih.gov/pubmed/15466696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404180101
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