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Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors
Stable genetic modification of adult stem cells is fundamental for both developmental studies and therapeutic purposes. Using in vivo marking studies, we showed that injection of lentiviral vectors (LVs) into the subventricular zone of the adult mouse brain enables efficient gene transfer into long-...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522006/ https://ncbi.nlm.nih.gov/pubmed/15466696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404180101 |
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