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Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

Stable genetic modification of adult stem cells is fundamental for both developmental studies and therapeutic purposes. Using in vivo marking studies, we showed that injection of lentiviral vectors (LVs) into the subventricular zone of the adult mouse brain enables efficient gene transfer into long-...

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Hlavní autoři: Consiglio, Antonella, Gritti, Angela, Dolcetta, Diego, Follenzi, Antonia, Bordignon, Claudio, Gage, Fred H., Vescovi, Angelo Luigi, Naldini, Luigi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC522006/
https://ncbi.nlm.nih.gov/pubmed/15466696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404180101
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