Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen

The cancer-germline gene MAGE-3 codes for tumor-specific antigens recognized on many tumors by T lymphocytes. A MAGE-3 antigen presented by HLA-A1 has been used in several vaccination trials on metastatic melanoma patients. Only a small minority of patients have shown evidence of tumor regression. A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lonchay, Christophe, van der Bruggen, Pierre, Connerotte, Thierry, Hanagiri, Takeshi, Coulie, Pierre, Colau, Didier, Lucas, Sophie, Van Pel, Aline, Thielemans, Kris, van Baren, Nicolas, Boon, Thierry
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Colloquium
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC521999/
https://ncbi.nlm.nih.gov/pubmed/15452345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405743101
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