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Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen
The cancer-germline gene MAGE-3 codes for tumor-specific antigens recognized on many tumors by T lymphocytes. A MAGE-3 antigen presented by HLA-A1 has been used in several vaccination trials on metastatic melanoma patients. Only a small minority of patients have shown evidence of tumor regression. A...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521999/ https://ncbi.nlm.nih.gov/pubmed/15452345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405743101 |
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