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Lamellipodial actin mechanically links myosin activity with adhesion site formation
Cell motility proceeds by cycles of edge protrusion, adhesion and retraction. Whether these functions are coordinated by biochemical or biomechanical processes is unknown. We find that myosin II pulls the rear of the lamellipodial actin network, causing upward bending, edge retraction and initiation...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5219974/ https://ncbi.nlm.nih.gov/pubmed/17289574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.039 |
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