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Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications

Glatiramer acetate (GA, Copaxone, Copolymer 1) is an approved drug for the treatment of multiple sclerosis and is highly effective in the suppression of experimental autoimmune encephalomyelitis in various species. The mode of action of GA is by initial strong promiscuous binding to MHC molecules an...

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Détails bibliographiques
Auteurs principaux: Arnon, Ruth, Aharoni, Rina
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC521994/
https://ncbi.nlm.nih.gov/pubmed/15371592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404887101
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