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Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications
Glatiramer acetate (GA, Copaxone, Copolymer 1) is an approved drug for the treatment of multiple sclerosis and is highly effective in the suppression of experimental autoimmune encephalomyelitis in various species. The mode of action of GA is by initial strong promiscuous binding to MHC molecules an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521994/ https://ncbi.nlm.nih.gov/pubmed/15371592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404887101 |
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