RBM5 inhibits tumorigenesis of gliomas through inhibition of Wnt/β-catenin signaling and induction of apoptosis

BACKGROUND: Gliomas are one of the most common malignant brain tumors and bring a big threat to human life as traditional therapy is unsatisfactory. RBM5 was a RNA-binding motif protein and was reported as a tumor suppressor. But the role of RBM5 in gliomas was unknown. METHODS: The mRNA level of RB...

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Vydáno v:World J Surg Oncol
Hlavní autoři: Jiang, Yuanpei, Sheng, Hongling, Meng, Lei, Yue, Hongsheng, Li, Bo, Zhang, Aijun, Dong, Yanan, Liu, Yuguang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219762/
https://ncbi.nlm.nih.gov/pubmed/28061901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-016-1084-1
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