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WNT974 Inhibits Proliferation, Induces Apoptosis, and Enhances Chemosensitivity to Doxorubicin in Lymphoma Cells by Inhibiting Wnt/β-Catenin Signaling
BACKGROUND: Upregulation of the Wnt/β-catenin pathway has been demonstrated to promote tumor proliferation and chemoresistance in lymphoma. Our objective was to evaluate the effect of the Wnt/β-catenin pathway inhibitor WNT974 in lymphoma cells. MATERIAL/METHODS: Human lymphoma cell lines HUT-78 and...
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| Pubblicato in: | Med Sci Monit |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
International Scientific Literature, Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7346748/ https://ncbi.nlm.nih.gov/pubmed/32597418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.923799 |
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