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The engineered Salmonella typhimurium inhibits tumorigenesis in advanced glioma

OBJECTIVE: To explore the antitumor role of the attenuated Salmonella typhimurium ΔppGpp with inducible cytolysin A (ClyA) in advanced stage of glioma. MATERIALS AND METHODS: The C6 rat glioma cells were orthotopically implanted by surgery into the caudate nucleus of rat brains. The rats were then r...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Jian-qiang, Zhan, Yue-fu, Wang, Wei, Jiang, Sheng-nan, Li, Xiang-ying
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592054/
https://ncbi.nlm.nih.gov/pubmed/26451114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S86899
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