Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression

Uncovering new therapeutic targets for renal fibrosis holds promise for the treatment of chronic kidney diseases. Bromodomain and extra-terminal (BET) protein inhibitors have been shown to effectively ameliorate pathological fibrotic responses. However, the pharmacological effects and underlying mec...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Redox Biol
Hlavní autoři: Zhou, Baoshang, Mu, Jiao, Gong, Yi, Lu, Caibao, Zhao, Youguang, He, Ting, Qin, Zhexue
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219604/
https://ncbi.nlm.nih.gov/pubmed/28063381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.031
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky