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Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium Have Low Levels of Heme and a Reduced Rate of Respiration and Are Sensitive to Oxidative Stress

Mutations in the translation elongation factor G (EF-G) make Salmonella enterica serovar Typhimurium resistant to the antibiotic fusidic acid. Fus(r) mutants are hypersensitive to oxidative stress and rapidly lose viability in the presence of hydrogen peroxide. We show that this phenotype is associa...

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Autores principales: Macvanin, Mirjana, Ballagi, Andras, Hughes, Diarmaid
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC521928/
https://ncbi.nlm.nih.gov/pubmed/15388448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3877-3883.2004
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