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Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium Have Low Levels of Heme and a Reduced Rate of Respiration and Are Sensitive to Oxidative Stress

Mutations in the translation elongation factor G (EF-G) make Salmonella enterica serovar Typhimurium resistant to the antibiotic fusidic acid. Fus(r) mutants are hypersensitive to oxidative stress and rapidly lose viability in the presence of hydrogen peroxide. We show that this phenotype is associa...

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Detalhes bibliográficos
Main Authors: Macvanin, Mirjana, Ballagi, Andras, Hughes, Diarmaid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521928/
https://ncbi.nlm.nih.gov/pubmed/15388448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3877-3883.2004
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