Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium with Low Fitness In Vivo Are Defective in RpoS Induction

Mutants of Salmonella enterica serovar Typhimurium resistant to fusidic acid (Fus(r)) have mutations in fusA, the gene encoding translation elongation factor G (EF-G). Most Fus(r) mutants have reduced fitness in vitro and in vivo, in part explained by mutant EF-G slowing the rate of protein synthesi...

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Bibliografische gegevens
Hoofdauteurs: Macvanin, Mirjana, Björkman, Johanna, Eriksson, Sofia, Rhen, Mikael, Andersson, Dan I., Hughes, Diarmaid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296224/
https://ncbi.nlm.nih.gov/pubmed/14638476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3743-3749.2003
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