Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium with Low Fitness In Vivo Are Defective in RpoS Induction

Mutants of Salmonella enterica serovar Typhimurium resistant to fusidic acid (Fus(r)) have mutations in fusA, the gene encoding translation elongation factor G (EF-G). Most Fus(r) mutants have reduced fitness in vitro and in vivo, in part explained by mutant EF-G slowing the rate of protein synthesi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Macvanin, Mirjana, Björkman, Johanna, Eriksson, Sofia, Rhen, Mikael, Andersson, Dan I., Hughes, Diarmaid
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3743-3749.2003
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