Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium with Low Fitness In Vivo Are Defective in RpoS Induction

Mutants of Salmonella enterica serovar Typhimurium resistant to fusidic acid (Fus(r)) have mutations in fusA, the gene encoding translation elongation factor G (EF-G). Most Fus(r) mutants have reduced fitness in vitro and in vivo, in part explained by mutant EF-G slowing the rate of protein synthesi...

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Главные авторы: Macvanin, Mirjana, Björkman, Johanna, Eriksson, Sofia, Rhen, Mikael, Andersson, Dan I., Hughes, Diarmaid
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Mechanisms of Resistance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC296224/
https://ncbi.nlm.nih.gov/pubmed/14638476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3743-3749.2003
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