Fusidic Acid-Resistant Mutants of Salmonella enterica Serovar Typhimurium with Low Fitness In Vivo Are Defective in RpoS Induction

Mutants of Salmonella enterica serovar Typhimurium resistant to fusidic acid (Fus(r)) have mutations in fusA, the gene encoding translation elongation factor G (EF-G). Most Fus(r) mutants have reduced fitness in vitro and in vivo, in part explained by mutant EF-G slowing the rate of protein synthesi...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Macvanin, Mirjana, Björkman, Johanna, Eriksson, Sofia, Rhen, Mikael, Andersson, Dan I., Hughes, Diarmaid
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2003
Gaiak:	Mechanisms of Resistance
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3743-3749.2003
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