Inhibition of Human Cytomegalovirus Replication by Benzimidazole Nucleosides Involves Three Distinct Mechanisms

The benzimidazole nucleosides 2-bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole (BDCRB) and 2-isopropylamino-5,6-dichloro-1-(β-l-ribofuranosyl)benzimidazole (1263W94, or maribavir) are potent and selective inhibitors of human cytomegalovirus (HCMV) replication. These inhibitors act by two diff...

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Main Authors: Evers, David L., Komazin, Gloria, Ptak, Roger G., Shin, Dongjin, Emmer, Brian T., Townsend, Leroy B., Drach, John C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC521925/
https://ncbi.nlm.nih.gov/pubmed/15388453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3918-3927.2004
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