Susceptibilities of Human Cytomegalovirus Clinical Isolates and Other Herpesviruses to New Acetylated, Tetrahalogenated Benzimidazole d-Ribonucleosides

Recently we characterized two inhibitors targeting the human cytomegalovirus (HCMV) terminase, 2-bromo-4,5,6-trichloro-1-(2,3,5-tri-O-acetyl-β-d-ribofuranosyl) benzimidazole (BTCRB) and 2,4,5,6-tetrachloro-1-(2,3,5-tri-O-acetyl-β-d-ribofuranosyl) benzimidazole (Cl(4)RB). The terminase consists of th...

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Detalhes bibliográficos
Main Authors: Hwang, Jae-Seon, Schilf, Rita, Drach, John C., Townsend, Leroy B., Bogner, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786319/
https://ncbi.nlm.nih.gov/pubmed/19786605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00809-09
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