Mutant Prevention Concentrations for Single-Step Fluoroquinolone-Resistant Mutants of Wild-Type, Efflux-Positive, or ParC or GyrA Mutation-Containing Streptococcus pneumoniae Isolates

Three fluoroquinolone-susceptible and five fluoroquinolone-resistant (two with ParC Ser79Phe mutations, one with a GyrA Ser81Phe mutation, and two that were efflux positive) Streptococcus pneumoniae isolates were exposed to one, two, four, eight, and sixteen times the MICs of ciprofloxacin, gatiflox...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Smith, Heather J., Walters, Michael, Hisanaga, Tamiko, Zhanel, George G., Hoban, Daryl J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388458/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.3954-3958.2004
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