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Mutant Prevention Concentrations for Single-Step Fluoroquinolone-Resistant Mutants of Wild-Type, Efflux-Positive, or ParC or GyrA Mutation-Containing Streptococcus pneumoniae Isolates

Three fluoroquinolone-susceptible and five fluoroquinolone-resistant (two with ParC Ser79Phe mutations, one with a GyrA Ser81Phe mutation, and two that were efflux positive) Streptococcus pneumoniae isolates were exposed to one, two, four, eight, and sixteen times the MICs of ciprofloxacin, gatiflox...

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Autori principali: Smith, Heather J., Walters, Michael, Hisanaga, Tamiko, Zhanel, George G., Hoban, Daryl J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521923/
https://ncbi.nlm.nih.gov/pubmed/15388458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3954-3958.2004
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