Azole Resistance in Candida glabrata: Coordinate Upregulation of Multidrug Transporters and Evidence for a Pdr1-Like Transcription Factor

Candida glabrata has emerged as a common cause of fungal infection. This yeast has intrinsically low susceptibility to azole antifungals such as fluconazole, and mutation to frank azole resistance during treatment has been documented. Potential resistance mechanisms include changes in expression or...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Vermitsky, John-Paul, Edlind, Thomas D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388433/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.3773-3781.2004
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