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Differences in the recruitment of DNA repair proteins at subtelomeric and interstitial I-SceI endonuclease-induced DNA double-strand breaks

Telomeres are nucleoprotein structures that are required to protect chromosome ends. Dysfunctional telomeres are recognized as DNA double-strand breaks (DSBs), and elicit the activation of a DNA damage response (DDR). We have previously reported that DSBs near telomeres are poorly repaired, resultin...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Silva, Bárbara Alcaraz, Jones, Trevor J., Murnane, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218964/
https://ncbi.nlm.nih.gov/pubmed/27842255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.10.008
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