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I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila.

As a step toward the development of a homologous recombination system in Drosophila, we have developed a methodology to target double-strand breaks (DSBs) to a specific position in the Drosophila genome. This method uses the mitochondrial endonuclease I-SceI that recognizes and cuts an 18-bp restric...

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Main Authors: Bellaiche, Y, Mogila, V, Perrimon, N
格式: Artigo
語言:Inglês
出版: 1999
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460675/
https://ncbi.nlm.nih.gov/pubmed/10388822
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