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Efficacy of Posaconazole in a Murine Model of Central Nervous System Aspergillosis

Human central nervous system (CNS) aspergillosis has >90% mortality. We compared posaconazole with other antifungals for efficacy against murine CNS aspergillosis. All tested regimens of posaconazole were equivalent to those of amphotericin B and superior in prolonging survival and reducing CFU t...

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Hlavní autoři: Imai, Jackie K., Singh, Gaurav, Clemons, Karl V., Stevens, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC521895/
https://ncbi.nlm.nih.gov/pubmed/15388482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4063-4066.2004
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