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Experimental Central Nervous System Aspergillosis Therapy: Efficacy, Drug Levels and Localization, Immunohistopathology, and Toxicity

We have shown previously that high-dose lipid amphotericin preparations are not more efficacious than lower doses in aspergillosis. We studied toxicity, drug concentrations and localization, and quantitative infection concurrently, using a 4-day model of central nervous system (CNS) aspergillosis to...

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Hlavní autoři: Clemons, Karl V., Schwartz, Julie A., Stevens, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421548/
https://ncbi.nlm.nih.gov/pubmed/22687510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06015-11
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