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Experimental Evidence That Granulocyte Transfusions Are Efficacious in Treatment of Neutropenic Hosts with Pulmonary Aspergillosis

Although polymorphonuclear leukocytes (PMNs) are powerfully anti-Aspergillus, transfusion therapy remains controversial, with conflicting results, and experimental support has been lacking. We devised a pulmonary infection model in neutropenic BALB/c mice, used an antibacterial regimen to prevent co...

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Detalhes bibliográficos
Main Authors: Martinez, Marife, Chen, Vicky, Tong, Ann-Jay, Hamilton, Kelsey, Clemons, Karl V., Stevens, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623303/
https://ncbi.nlm.nih.gov/pubmed/23380731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02533-12
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