Efficacy of Caspofungin against Central Nervous System Aspergillus fumigatus Infection in Mice Determined by TaqMan PCR and CFU Methods

We have reported previously that prolonged caspofungin (CAS) dosing enhances survival in a murine model of central nervous system aspergillosis. In this study we determined by quantitative PCR (qPCR) and CFU enumeration whether CAS could reduce fungal burdens, prior to the deaths of untreated animal...

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Autores principales: Singh, Gaurav, Imai, Jackie, Clemons, Karl V., Stevens, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068651/
https://ncbi.nlm.nih.gov/pubmed/15793114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1369-1376.2005
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