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Efficacy of Caspofungin against Central Nervous System Aspergillus fumigatus Infection in Mice Determined by TaqMan PCR and CFU Methods

We have reported previously that prolonged caspofungin (CAS) dosing enhances survival in a murine model of central nervous system aspergillosis. In this study we determined by quantitative PCR (qPCR) and CFU enumeration whether CAS could reduce fungal burdens, prior to the deaths of untreated animal...

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Detalles Bibliográficos
Main Authors: Singh, Gaurav, Imai, Jackie, Clemons, Karl V., Stevens, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068651/
https://ncbi.nlm.nih.gov/pubmed/15793114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1369-1376.2005
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