A Series of Diaryltriazines and Diarylpyrimidines Are Highly Potent Nonnucleoside Reverse Transcriptase Inhibitors with Possible Applications as Microbicides

An in vitro model of monocyte-derived dendritic cells (MO-DC) and CD4(+) T cells, representing the primary targets of sexual human immunodeficiency virus (HIV) transmission, was used to evaluate the antiviral and immune suppressive activity of new classes of nonnucleoside reverse transcriptase inhib...

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Bibliographic Details
Main Authors: Van Herrewege, Yven, Vanham, Guido, Michiels, Jo, Fransen, Katrien, Kestens, Luc, Andries, Koen, Janssen, Paul, Lewi, Paul
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC521893/
https://ncbi.nlm.nih.gov/pubmed/15388420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3684-3689.2004
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