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A Series of Diaryltriazines and Diarylpyrimidines Are Highly Potent Nonnucleoside Reverse Transcriptase Inhibitors with Possible Applications as Microbicides

An in vitro model of monocyte-derived dendritic cells (MO-DC) and CD4(+) T cells, representing the primary targets of sexual human immunodeficiency virus (HIV) transmission, was used to evaluate the antiviral and immune suppressive activity of new classes of nonnucleoside reverse transcriptase inhib...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Van Herrewege, Yven, Vanham, Guido, Michiels, Jo, Fransen, Katrien, Kestens, Luc, Andries, Koen, Janssen, Paul, Lewi, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388420/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.3684-3689.2004
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