The DIAN-TU Next Generation Alzheimer’s prevention trial: adaptive design and disease progression model

INTRODUCTION: The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) trial is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first tw...

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Veröffentlicht in:Alzheimers Dement
Hauptverfasser: Bateman, Randall J., Benzinger, Tammie L., Berry, Scott, Clifford, David B., Duggan, Cynthia, Fagan, Anne M., Fanning, Kathleen, Farlow, Martin R., Hassenstab, Jason, McDade, Eric M., Mills, Susan, Paumier, Katrina, Quintana, Melanie, Salloway, Stephen P., Santacruz, Anna, Schneider, Lon S., Wang, Guoqiao, Xiong, Chengjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218895/
https://ncbi.nlm.nih.gov/pubmed/27583651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.07.005
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