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Replacement of Thymidine by a Modified Base in the E. coli genome
Prokaryotic and eukaryotic genomic DNA is comprised of the four building blocks A, G, C and T. We have begun to explore the consequences of replacing a large fraction or all of a nucleoside in genomic DNA with a modified nucleoside. As a first step we have investigated the possibility of replacement...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5218517/ https://ncbi.nlm.nih.gov/pubmed/27213685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03904 |
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