Structural and Virological Studies of the Stages of Virus Replication That Are Affected by Antirhinovirus Compounds

Pleconaril is a broad-spectrum antirhinovirus and antienterovirus compound that binds into a hydrophobic pocket within viral protein 1, stabilizing the capsid and resulting in the inhibition of cell attachment and RNA uncoating. When crystals of human rhinovirus 16 (HRV16) and HRV14 are incubated wi...

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Bibliografiske detaljer
Main Authors: Zhang, Ying, Simpson, Alan A., Ledford, Rebecca M., Bator, Carol M., Chakravarty, Sugoto, Skochko, Gregory A., Demenczuk, Tina M., Watanyar, Adiba, Pevear, Daniel C., Rossmann, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521849/
https://ncbi.nlm.nih.gov/pubmed/15452226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11061-11069.2004
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