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Structural and Virological Studies of the Stages of Virus Replication That Are Affected by Antirhinovirus Compounds

Pleconaril is a broad-spectrum antirhinovirus and antienterovirus compound that binds into a hydrophobic pocket within viral protein 1, stabilizing the capsid and resulting in the inhibition of cell attachment and RNA uncoating. When crystals of human rhinovirus 16 (HRV16) and HRV14 are incubated wi...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Zhang, Ying, Simpson, Alan A., Ledford, Rebecca M., Bator, Carol M., Chakravarty, Sugoto, Skochko, Gregory A., Demenczuk, Tina M., Watanyar, Adiba, Pevear, Daniel C., Rossmann, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15452226/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.20.11061-11069.2004
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