Triaryl Pyrazoline Compound Inhibits Flavivirus RNA Replication

Triaryl pyrazoline {[5-(4-chloro-phenyl)-3-thiophen-2-yl-4,5-dihydro-pyrazol-1-yl]-phenyl-methanone} inhibits flavivirus infection in cell culture. The inhibitor was identified through high-throughput screening of a compound library using a luciferase-expressing West Nile (WN) virus infection assay....

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Autori principali: Puig-Basagoiti, Francesc, Tilgner, Mark, Forshey, Brett M., Philpott, Sean M., Espina, Noel G., Wentworth, David E., Goebel, Scott J., Masters, Paul S., Falgout, Barry, Ren, Ping, Ferguson, David M., Shi, Pei-Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426921/
https://ncbi.nlm.nih.gov/pubmed/16569847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1320-1329.2006
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