High-Throughput Assays Using a Luciferase-Expressing Replicon, Virus-Like Particles, and Full-Length Virus for West Nile Virus Drug Discovery

Many flaviviruses cause significant human disease worldwide. The development of flavivirus chemotherapy requires reliable high-throughput screening (HTS) assays. Although genetic systems have been developed for many flaviviruses, their usage in antiviral HTS assays has not been well explored. Here w...

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Detalles Bibliográficos
Main Authors: Puig-Basagoiti, Francesc, Deas, Tia S., Ren, Ping, Tilgner, Mark, Ferguson, David M., Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315944/
https://ncbi.nlm.nih.gov/pubmed/16304161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4980-4988.2005
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