Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous group of hematopoietic stem cell disorders characterized by defects in myeloid differentiation and increased proliferation of neoplastic hematopoietic precursor cells. Outcomes for patients with AML remain poor, highlighting the need for novel treatmen...

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Pubblicato in:PLoS One
Autori principali: Min, Chengyin, Moore, Nathan, Shearstone, Jeffrey R., Quayle, Steven N., Huang, Pengyu, van Duzer, John H., Jarpe, Matthew B., Jones, Simon S., Yang, Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218480/
https://ncbi.nlm.nih.gov/pubmed/28060870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169128
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