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Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous group of hematopoietic stem cell disorders characterized by defects in myeloid differentiation and increased proliferation of neoplastic hematopoietic precursor cells. Outcomes for patients with AML remain poor, highlighting the need for novel treatmen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Min, Chengyin, Moore, Nathan, Shearstone, Jeffrey R., Quayle, Steven N., Huang, Pengyu, van Duzer, John H., Jarpe, Matthew B., Jones, Simon S., Yang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218480/
https://ncbi.nlm.nih.gov/pubmed/28060870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169128
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