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Antioxidant Treatment Reduces Expansion and Contraction of Antigen-Specific CD8(+) T Cells during Primary but Not Secondary Viral Infection
During many viral infections, antigen-specific CD8(+) T cells undergo large-scale expansion. After viral clearance, the vast majority of effector CD8(+) T cells undergo apoptosis. Previous studies have implicated reactive oxygen intermediates (ROI) in lymphocyte apoptosis. The purpose of the experim...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521823/ https://ncbi.nlm.nih.gov/pubmed/15452243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11246-11257.2004 |
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