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An N-Terminal Amphipathic Helix in Hepatitis C Virus (HCV) NS4B Mediates Membrane Association, Correct Localization of Replication Complex Proteins, and HCV RNA Replication

Like other positive-strand RNA viruses, hepatitis C virus (HCV) is believed to replicate its RNA in association with host cell cytoplasmic membranes. Because of its association with such membranes, NS4B, one of the virus's nonstructural proteins, may play an important role in this process, alth...

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Detalhes bibliográficos
Main Authors: Elazar, Menashe, Liu, Ping, Rice, Charles M., Glenn, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521809/
https://ncbi.nlm.nih.gov/pubmed/15452261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11393-11400.2004
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