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Calmodulin Gates Aquaporin 0 Permeability through a Positively Charged Cytoplasmic Loop

Aquaporin 0 (AQP0), the major intrinsic protein of the eye lens, plays a vital role in maintaining lens clarity by facilitating the transport of water across lens fiber cell membranes. AQP0 reduces its osmotic water permeability constant (P(f)) in response to increases in the external calcium concen...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fields, James B., Németh-Cahalan, Karin L., Freites, J. Alfredo, Vorontsova, Irene, Hall, James E., Tobias, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217678/
https://ncbi.nlm.nih.gov/pubmed/27660387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.743724
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