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Cooperativity and allostery in aquaporin 0 regulation by Ca(2+)
Aquaporin 0 (AQP0) is essential for eye lens homeostasis as is regulation of its water permeability by Ca(2+), which occurs through interactions with Calmodulin (CaM), but the underlying molecular mechanisms are not well understood. Here, we use molecular dynamics (MD) simulations on the microsecond...
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| Опубликовано в: : | Biochim Biophys Acta Biomembr |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437002/ https://ncbi.nlm.nih.gov/pubmed/30802427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2019.02.007 |
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