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Molecular Basis of pH and Ca(2+) Regulation of Aquaporin Water Permeability

Aquaporins facilitate the diffusion of water across cell membranes. We previously showed that acid pH or low Ca(2+) increase the water permeability of bovine AQP0 expressed in Xenopus oocytes. We now show that external histidines in loops A and C mediate the pH dependence. Furthermore, the position...

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Bibliografische gegevens
Hoofdauteurs: Németh-Cahalan, Karin L., Kalman, Katalin, Hall, James E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234493/
https://ncbi.nlm.nih.gov/pubmed/15078916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308990
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