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Molecular Basis of pH and Ca(2+) Regulation of Aquaporin Water Permeability
Aquaporins facilitate the diffusion of water across cell membranes. We previously showed that acid pH or low Ca(2+) increase the water permeability of bovine AQP0 expressed in Xenopus oocytes. We now show that external histidines in loops A and C mediate the pH dependence. Furthermore, the position...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234493/ https://ncbi.nlm.nih.gov/pubmed/15078916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308990 |
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