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In Vivo Analysis of Aquaporin 0 Function in Zebrafish: Permeability Regulation Is Required for Lens Transparency

PURPOSE. The zebrafish lens is well suited for studies of physiology and development due to its rapid formation in the embryo and genetic accessibility. Aquaporin 0 (AQP0), a lens-specific membrane protein, is required for lens clarity. Zebrafish have two copies of AQP0 (Aqp0a and b), whereas mammal...

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Detalhes bibliográficos
Main Authors: Clemens, Daniel M., Németh-Cahalan, Karin L., Trinh, Lien, Zhang, Tailin, Schilling, Thomas F., Hall, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729242/
https://ncbi.nlm.nih.gov/pubmed/23800763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12337
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