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In Vivo Analysis of Aquaporin 0 Function in Zebrafish: Permeability Regulation Is Required for Lens Transparency

PURPOSE. The zebrafish lens is well suited for studies of physiology and development due to its rapid formation in the embryo and genetic accessibility. Aquaporin 0 (AQP0), a lens-specific membrane protein, is required for lens clarity. Zebrafish have two copies of AQP0 (Aqp0a and b), whereas mammal...

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Hlavní autoři: Clemens, Daniel M., Németh-Cahalan, Karin L., Trinh, Lien, Zhang, Tailin, Schilling, Thomas F., Hall, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729242/
https://ncbi.nlm.nih.gov/pubmed/23800763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12337
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