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PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells

BACKGROUND: Lymphatic metastasis, facilitated by lymphangiogenesis is a common occurrence in breast cancer, the molecular mechanisms remaining incompletely understood. We had earlier shown that cyclooxygenase (COX)-2 expression by human or murine breast cancer cells promoted lymphangiogenesis and ly...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Nandi, Pinki, Girish, Gannareddy V., Majumder, Mousumi, Xin, Xiping, Tutunea-Fatan, Elena, Lala, Peeyush K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217626/
https://ncbi.nlm.nih.gov/pubmed/28056899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-3018-2
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