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Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5

STAT5, a member of the family of Signal Transducers and Activators of Transcription senses cytokines and controls the biology of cell lineages, including mammary, liver and T cells. Here we show that STAT5 activates lineage-specific and widely expressed genes through different mechanisms. STAT5 pref...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Zeng, Xianke, Willi, Michaela, Shin, Ha Youn, Hennighausen, Lothar, Wang, Chaochen
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217531/
https://ncbi.nlm.nih.gov/pubmed/28009300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.079
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