The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)

BACKGROUND: ICAM-1 is a major receptor for ~60% of human rhinoviruses, and non-typeable Haemophilus influenzae, two major pathogens in COPD. Increased cell-surface expression of ICAM-1 in response to tobacco smoke exposure has been suggested. We have investigated epithelial ICAM-1 expression in both...

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Veröffentlicht in:Respir Res
Hauptverfasser: Shukla, Shakti Dhar, Mahmood, Malik Quasir, Weston, Steven, Latham, Roger, Muller, Hans Konrad, Sohal, Sukhwinder Singh, Walters, Eugene Haydn
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217320/
https://ncbi.nlm.nih.gov/pubmed/28056984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0483-8
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