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β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction

COPD is characterised by poorly reversible airflow obstruction usually due to cigarette smoking. The transcription factor clusters of β-catenin/Snail1/Twist has been implicated in the process of epithelial mesenchymal transition (EMT), an intermediate between smoking and airway fibrosis, and indeed...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Mahmood, Malik Quasir, Walters, Eugene Haydn, Shukla, Shakti D., Weston, Steve, Muller, Hans Konrad, Ward, Chris, Sohal, Sukhwinder Singh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589881/
https://ncbi.nlm.nih.gov/pubmed/28883453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11375-x
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