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Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction

BACKGROUND: Small airway fibrosis is the main contributor in airflow obstruction in chronic obstructive pulmonary disease. Epithelial mesenchymal transition (EMT) has been implicated in this process, and in large airways, is associated with angiogenesis, ie, Type-3, which is classically promalignant...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Mahmood, Malik Quasir, Sohal, Sukhwinder Singh, Shukla, Shakti Dhar, Ward, Chris, Hardikar, Ashutosh, Noor, Wan Danial, Muller, Hans Konrad, Knight, Darryl A, Walters, Eugene Haydn
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531032/
https://ncbi.nlm.nih.gov/pubmed/26346976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S81032
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