CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants

Double-strand breaks (DSBs) are one of the most harmful DNA lesions. Cells utilize two main pathways for DSB repair: homologous recombination (HR) and nonhomologous end-joining (NHEJ). NHEJ can be subdivided into the KU-dependent classical NHEJ (c-NHEJ) and the more error-prone KU-independent backup...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Shen, Hexi, Strunks, Gary D., Klemann, Bart J. P. M., Hooykaas, Paul J. J., de Pater, Sylvia
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217109/
https://ncbi.nlm.nih.gov/pubmed/27866150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035204
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