Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

BACKGROUND: Glioblastomas (GBM) present a high cellular heterogeneity with conspicuous necrotic regions associated with hypoxia, which is related to tumor aggressiveness. GBM tumors exhibit high glycolytic metabolism with increased lactate production that is extruded to the tumor microenvironment th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Miranda-Gonçalves, Vera, Granja, Sara, Martinho, Olga, Honavar, Mrinalini, Pojo, Marta, Costa, Bruno M., Pires, Manuel M., Pinheiro, Célia, Cordeiro, Michelle, Bebiano, Gil, Costa, Paulo, Reis, Rui M., Baltazar, Fátima
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216802/
https://ncbi.nlm.nih.gov/pubmed/27331625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker